Nf-Light Simoa Assay Advantage Kit

Nf-Light Simoa Assay Advantage Kit



The Simoa NF -light™ assay is a digital immunoassay for the quantitative determination of NfL in serum, plasma and CSF. The antibodies also cross react with murine, bovine, and macaque NfL epitopes, and the assay can be used for research with these species.


animal-sourced NF -light. Non-native and animal forms of NF -light have been found to interact differently with sample matrix than native NF -light, which can lead to poor recovery or linearity results. The Simoa NF -light (SR-X) assay kit is formulated for use on the SR-X platform only. Data in this document was, This assay kit has been designed with a new formulation of sample diluent to prevent bead aggregation in plasma sample matrix. Quanterix recommends researchers use this assay kit (item#103400) for SR-X studies in place of the original Simoa NF -light assay kit (item#103186).


Simoa ® Assay Kits Ready-to-use Simoa ® kits contain all the reagents necessary to run your assay on the HD-1, HD-X , SR-X or SP-X platforms. Our broad portfolio of available kits spans multiple therapeutic areas including cardiology, infectious disease, inflammation, neurology, and oncology.


There is a need to link historical ELISA data that use bovine NfL to that of Simoa using a recombinant human (rhuman) NfL standard. Results/Methodology: The Simoa NF -light ® Advantage Kit was validated for CSF and qualified for serum and plasma, using both rhuman and bovine NfL calibrators. Matched CSF, serum and plasma samples from 112 …


NF- LIGHT ™ – Quanterix, Products – UmanDiagnostics, Simoa Assay Services: Ultra-Sensitive Biomarker Testing, The Simoa NF -light ® assay is a digital immunoassay for the quantitative determination of NF-L in serum, plasma and CSF. The antibodies (Uman Diagnostics, Umeå Sweden) also cross react with murine, bovine, and macaque NF-L epitopes, and the assay can be used for research with these species.


Simoa Advantage assay performance and precision specifications are determined according to Clinical Laboratory Standards Institute guidelines for consistency, sensitivity, precision, and robustness. Details are included in each kit ’s product insert and certificate of analysis.


NF -Light ELISA Assay The NF -light® (Neurofilament light) ELISA allows fast quantification (<3 hours) of neurofilament light in cerebrospinal fluid. The amount of sample is small (50 ?l) and the standard curve ranges from 100-10000 pg/ml allowing for direct measurement of NF-L.82 rows  · PBL's Ultrasensitive Biomarker Testing Assay Services take advantage of the benefits of …

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